• PU>> do endoscopy (age>55 ys or progressive course) and H.pylori test> If DU medical ttt for 2 month and don’t repeat endoscopy unless still symptomatic or there was perforation in 1st endoscopy. If GU u have to take biopsy and repeat endoscopy
• ZES: multiple PU in stomach, duodenum and jejunum. High gastrin, CT abd. ttt by high dose PPI
• H.pylori: Ass. With PU, Gastric adenocarcinoma and gastric lymphoma (ttt by PPI in 1st stages) for screening>> rapid urea breath test (best), or serum IgG. For diagnosis stool antigens for it (patient off PPI for 2 ws), Biopsy (urea test, histopathology and culture)
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